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Pharmacy Dosage Simple Calculations- Please Need Help Now to learn

Discussion in 'Pharmacy' started by PrePharmStu2009, Jul 12, 2011.

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  1. PrePharmStu2009

    PrePharmStu2009 5+ Year Member

    Sep 8, 2009
    1. What does D5 1/2 NS mean?

    I know that 5 % dextrose is 5 g/100 ml right? so 1/2 NS does that imply 77 meq/ 1000 ml NaCl concentration?

    What if it is 1/4 NS 500 ml...
    What is the concentration the of Na Cl then

    2. Sodium Chloride comes in a concentration of 4 mEq/ml. How much NaCl must you add to sterile water to make the following solutions:

    1/4NS 250 ml NS 1000 ml , 1/2 NS 500 ml, 1/2 NS 1000 ml, 1/4 500 ml, NS 250 ml, NS 500 ml

    How do you do this problem? If someone can explain me the basic steps and show an example. How are concentrations based on volume. So for 1/4, 250 will concentration be 1/8 * (154) since 154 is normal and volume is reduced by 1/4 of 1000, so 1/4 NS???
    Last edited: Jul 15, 2011
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  3. type b pharmD

    type b pharmD 7+ Year Member

    Feb 24, 2009
    d5 1/2 NS = a solution containing 0.45% sodium chloride and 5% dextrose in sterile water.

    As for the making the bags. Just remember and think carefully about this .

    NS = 0.9% nacl = 154meq/L
    1/2NS = 0.45% nacl = 77meq/L
    1/4NS = 0.225% nacl = 38.5meq/L

    You dont need any more help than this. If you think hard and carefully about it, you will learn better and teach yourself new things.

    Calculating % to meqs conversions is annoying and for me takes like 10 minutes of reasoning through chemistry formulas and moles and milimoles. Most pharmacists I know recommend just memorizing meq's/L for some standard solutions.

    Oh, and btw: NS = normal saline. (0.9%, which is basically the same tonicity as the body's fluids.) 1/2NS is half of that, 1/4NS, 1/4, etc, etc, etc.
    Last edited: Jul 12, 2011
  4. PharmDstudent

    PharmDstudent 7+ Year Member

    Jan 8, 2007
    Thanks! I had to use those today. :p

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