physical findings between platelet and clot cascade

[tiedyeddog]

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I slightly remember there being a difference in physical findings between platelet disorders and coagulation cascade disorders?

I can't find the difference in FA. It's something like this:

clotting cascade: purpura, blood that blanches on touch the bleed
clotting: petechia, non-blanching, blah blah

anyone know what I am talking about??? Anyone know how it really goes???

 

[bangarang]

I slightly remember there being a difference in physical findings between platelet disorders and coagulation cascade disorders?

I can't find the difference in FA. It's something like this:

clotting cascade: purpura, blood that blanches on touch the bleed
clotting: petechia, non-blanching, blah blah

anyone know what I am talking about??? Anyone know how it really goes???

I think you're thinking of palpable vs. non-palpable purpura, which relates to vasculitis and platelet disorders respectively.

Vasculitis causes palpable purpura because it's related to blood vessel dysfunction, so when you press on it, the skin blanches (turns white) because you're compressing the vessels.

Non-palpable means the purpura is caused by some means other than the vessels like a platelet disorder, so when you compress the skin/vessels, it doesn't blanch. That's how I understood it, but perhaps someone else can clarify.

 

[Jonari]

Was it from Pathoma?

platelet disorders: ecchymoses, purpura, petechiae...mucosal hemorrhages, epistaxis
clotting cascade: bleeding into joints (hemarthrosis), associated with circumcisions/wisdom tooth repair

😕

 

[Jamiu22]

I slightly remember there being a difference in physical findings between platelet disorders and coagulation cascade disorders?

I can't find the difference in FA. It's something like this:

clotting cascade: purpura, blood that blanches on touch the bleed
clotting: petechia, non-blanching, blah blah

anyone know what I am talking about??? Anyone know how it really goes???

You are confusing multiple things...

• Platelet Disorder: primarily purpura (non-blanching), superficial bleeding (especially nose bleeds)
• Clotting Cascade: Late rebleeding (temporary platelet plugs are formed, but doesn't become permanent) - shows up as Hemarthrosis in large joints, and wisdom tooth (okay when you leave the dentist, but bleeds profusely when you rinse your mouth when at home).

Note: Blanching just means it's a vessel that you are pressing on e.g spider angioma, so when you press it, the lesion goes away (unlike purpura - this doesn't go away when pressed).

You can also use labs to differentiate this.

• Platelet: bleeding time
• Coagulation: PT & PTT

 

[tiedyeddog]

You are confusing multiple things...

• Platelet Disorder: primarily purpura (non-blanching), superficial bleeding (especially nose bleeds)
• Clotting Cascade: Late rebleeding (temporary platelet plugs are formed, but doesn't become permanent) - shows up as Hemarthrosis in large joints, and wisdom tooth (okay when you leave the dentist, but bleeds profusely when you rinse your mouth when at home).

Note: Blanching just means it's a vessel that you are pressing on e.g spider angioma, so when you press it, the lesion goes away (unlike purpura - this doesn't go away when pressed).

You can also use labs to differentiate this.

• Platelet: bleeding time
• Coagulation: PT & PTT

this is exactly what I was looking for, thanks for the explanation!