Assuming you get all these interviews, sure it's possible, depending on how much time and money you can spend. Mapquest will tell you how far it is btwn all these places and orbitz can get you in one city, out the other, and hotels in between. Of course, depending on the specialty, they may only offer a couple interview days (e.g., some ENT programs only have 2 interviews days for the whole season), and many of these may overlap or be full, making it difficult to string together all these interviews in a short period of time. But if you're doing something like IM, FP, or something not super competitive but with large residency classes (meaning they have to interview LOTS of people and, therefore, will have lots of interview days/slots), careful planning should make this possible. Of course, it could be argued that taking 2 or 3 separate trips might actually save time and money (and headaches) compared to spending extra days (hotels, food, expenses) out west just for the sake of getting them all done at once.