So I am currently looking for a job and have talked to some of my faculty and ex-faculty members about this topic. One of the attendings in my program who left for a PP recently was in academics for 10+ years and told me the following:
-Pros of academics: quality colleagues throughout different specialties, not only clinic based and can find career enrichment in working on projects/teaching residents, prestige, overall stability of practice (as in the university isn't going to close down on you)
-Cons of academics (main center position): low pay relative to PP colleagues, publish or perish with respect to promotion, increased bureaucracy and frustrating to see people who are clinically inept be rewarded for research but honestly are not good clinical doctors
-Pros of PP: ~40% pay increase after 2-3 years in comparison to academics, no pressure to publish, can be involved in overall radonc community (ASTRO committees, enroll on NRG trials, etc) if you are interested but no pressure,
-Cons of PP: referring docs can sometimes not be up to par with today's standard of care which is frustrating, some practices are purely eat what you kill so there is pressure to bring in "business" or court referring docs, some areas in the country have competitive markets (San Fran, LA, NYC, So Florida, etc) which can cause lack of practice stability (i.e. 21st century taking over)
Overall, my previous attending is super happy with his decision to leave academics and go into PP. He realized he wasn't cut out for the research demand. He didn't like it and it overall was what was determining his promotion and his career success. He did tell me a caveat to him being happy was he chose to join a large hospital based PP in a medium size city that wasn't super competitive. So he has a much better salary than when he was in academics but doesn't have the pressure to "practice build" and the practice is very financially stable.
Hope this helped.