I have the same problem. I graduated in 1994 with a Bio degree, so most of my prereqs. are OLD. Here is the feedback I received from California schools:
UCSF - the age of the prereqs. is not an issue, but they encouraged me to take more recent science courses.
UCSD - they would not accept any science prereq. older than 7 years.
USC - they would not accept any course older than 10 years.
Western - there is no time limit on prereqs.
UOP - I would have to take a core bio class and the 2nd semester of organic chemistry
Touro - no time limit on prereqs, but more recent courses are encouraged.
I recently finished Microbio and plan to take Anatomy, Physio, and possibly the 2nd semester of O-chem again. Hopefully, this will be enough to apply to UCSF, Western, and Touro. If I take a core bio course again, I can also apply to UOP.