I actually think that pre-meds are gaining more grey matter yearly, and their need to get in is growing proportionally. Pretty soon, you won't even get a secondary without advanced research in both molecular physics and quantum biological mechanics. Only people who play an instrument at a symphony level will be given serious consideration. And it's going to take both work with a Nobel Laureate, and a family legacy unto about six or seven generations, to get an interview. Beyond that, most people will get rejected anyway.
Get real, people. Pre-meds have allways been smart. They will continue to be smart. If you eat yourself up second guessing your chances, this is not the profession for you.
Because getting in is, I think, the easy part.