I would document on the hard copy that the medication is only available in an unbreakable package size, and then run it for the maximum days supply the insurance will allow. For a patient testing QD, I wouldn't give a box of 50 strips for a 30 day supply, when there is a box of 25 strips available. But if the smallest package size is 50 strips, then I would run that for 30 days, after documenting. Same with Premarin cream, run it for 30 days (or 90 days if their insurance allows) & document that the package can not be broken.
I would document on the hard copy that the medication is only available in an unbreakable package size, and then run it for the maximum days supply the insurance will allow. For a patient testing QD, I wouldn't give a box of 50 strips for a 30 day supply, when there is a box of 25 strips available. But if the smallest package size is 50 strips, then I would run that for 30 days, after documenting. The key to legality is giving the smallest available package size, giving 2 Proairs would not meet that criteria.