proton pump inhibitors

[jughead00]

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y r they associated with c.difficile, pneumonia and hip fractures?

thoughts?

 

[Greenbayslacker]

They decrease absorption of some nutrients, including Ca (-> hip fractures).
They decrease the acidic environment of the GI tract, causing decreased elimination of microbes (-> PNA).
The C. difficile connection is relatively recent and I do not know the reason for it.

 

[jughead00]

They decrease absorption of some nutrients, including Ca (-> hip fractures).
They decrease the acidic environment of the GI tract, causing decreased elimination of microbes (-> PNA).
The C. difficile connection is relatively recent and I do not know the reason for it.

that was helpful! thanks 🙂