May 25, 2015
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Q. Can anybody pls explain why patient with splenomegaly have thrombocytopeina and patient with asplenia or autosplenectomy have thrombocytosis.Thanks.
 

solitarius

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May 20, 2010
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Spleen stores platelets. A larger spleen can store more platelets --> less circulating --> penia.

Without a spleen, a storage space for platelets is gone --> more circulating platelets --> thrombocytosis.
 
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