q

[smalley]

how will you diff between pseudohypothyroidism an chronic renal failure ?

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[Tastebuds]

The etiologies are different.....secondary hypoparathyroidism (usually due to chronic renal disease) has decreased CA, increased phosphorous, and INCREASED PTH due to hypocalcemia. Pseudohypoparathyroidism, is an X-linked condition--according to RR Goljan (FA says AD condition---so I dont know) is due to the kidney not being responsive to PTH...in this condition you have NORMAL to increased PTH and hypocalcemia. I dont know of any other differences.

 

[smalley]

thanks tastebuds..but as the lab findings are the same in both..is there any other d/f which can help to distinguish between the two..?i havent come across any..

 

[Pinkertinkle]

thanks tastebuds..but as the lab findings are the same in both..is there any other d/f which can help to distinguish between the two..?i havent come across any..

Maybe something like history of renal failure? Or maybe physical exam with knuckle knuckle dimple dimple.