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I meant to go back to it but I can't find the id number. Here's what I got from memory:
A mother is a heterozygous carrier of Tay-Sachs (autosomal recessive). Her mutation is a rare point mutation (not the mutation seen in most forms of the disease). Her daughter is born with the disease and when genetic testing is done, she is found to have both the rare allele from her mother and the common Tay-Sachs mutation. The father is homozygous normal. How did the daughter get the common Tay-Sachs mutated allele?
There was no option for spontaneous mutation. I had it narrowed down to infidelity or unmasking of a silent allele. I could be wrong though and I don't remember the other options other than I confidently ruled them out. Any idea what is going on with this question? I can't even figure out what they're getting at.
A mother is a heterozygous carrier of Tay-Sachs (autosomal recessive). Her mutation is a rare point mutation (not the mutation seen in most forms of the disease). Her daughter is born with the disease and when genetic testing is done, she is found to have both the rare allele from her mother and the common Tay-Sachs mutation. The father is homozygous normal. How did the daughter get the common Tay-Sachs mutated allele?
There was no option for spontaneous mutation. I had it narrowed down to infidelity or unmasking of a silent allele. I could be wrong though and I don't remember the other options other than I confidently ruled them out. Any idea what is going on with this question? I can't even figure out what they're getting at.
