1..A 32-year-old woman complains of a sore throat, increasing fatigue, and shortness of breath for the past 3 days. On physical examination, her temperature is 101.5 F and her heart rate is 100, with no murmurs. A CBC with reticulocyte count shows 1500 white blood cells/mm3. The platelet count is 12 x 109/L. Bone marrow aspiration and biopsy demonstrates cellularity less than 25%, and the corrected reticulocyte count is less than 1%. Which of the following is the most likely diagnosis? A. Anemia of chronic disease B. Aplastic anemia C. Myelodysplasia with myelofibrosis D. Myelophthisic anemia E. Pure red cell aplasia 2..A donor liver arrives in New York from Chicago 7 hours after harvest. A biopsy is performed on arrival to check for ischemic injury. The sensitive oxidase P450 system is very susceptible to ischemia. In which of the following regions of the liver is this system located? A. Bile ducts B. Intermediate zone C. "Ito" cells D. Pericentral vein zone E. Periportal zone 3..During a routine pediatric examination, a 12-year-old boy is noted to be in growth arrest. The child is obese, and multiple small bruises are observed on his arms and legs. The patient has difficulty rising from a crouching position. Measurements of blood pressure demonstrates hypertension when compared to age-based standards. This patient most likely has which of the following? A. Diabetes mellitus B. Grave's disease C. Hypothyroidism D. Parathyroid adenoma E. Pituitary microadenoma 4..A 35-year-old woman dies suddenly. Autopsy findings are within normal limits except for the heart Which of the following is the most likely diagnosis? A. Acute endocarditis B. Calcification of the mitral anulus C. Marantic endocarditis D. Mitral valve prolapse E. Rheumatic valvular disease with explanations plzzzzz?