Quaternary Structure

[comed]

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In Kaplan, it notes Quaternary structure can "reduce the amount of DNA needed to encode the protein complex"
Can anyone explain that statement? Not sure how having an aggregate of smaller, globular peptide would equal less DNA needed.

Thanks in advance!

 

[lpp06]

If the sub units of the protein are redundant, it would require less DNA because each sub unit is encoded by the same sequence of DNA.

 

[aldol16]

Think of homodimers, homotrimers, and homo-multimers. How much DNA is required to encode them versus the monomers versus heterodimers, heterotrimers, etc.?