Hi, I read in UWorld (id#1516) that endothelin causes release of nitric oxide in the coronary arteries and thus leads to vasodilation. In question id #157, it says atrial natriuretic peptide and brain natriuretic peptide also cause vasodilation via the same mechanism of NO (increased cGMP). But that question also says ANP and BNP counteract the effects of endothelin. I don't understand this as they all three appear to do the same thing. Does anyone have any insight?
Thanks.
Thanks.