Question about ANP/BNP as countereffect to endothelin

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okokok

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Hi, I read in UWorld (id#1516) that endothelin causes release of nitric oxide in the coronary arteries and thus leads to vasodilation. In question id #157, it says atrial natriuretic peptide and brain natriuretic peptide also cause vasodilation via the same mechanism of NO (increased cGMP). But that question also says ANP and BNP counteract the effects of endothelin. I don't understand this as they all three appear to do the same thing. Does anyone have any insight?

Thanks.
 
Never mind - should've just looked it up before posting. In case anyone is interested, it's a question of where the endothelin is acting: "In addition to ETA and ETB receptors on the smooth muscle, ETB receptors are also found on the endothelium. When ET-1 binds to these endothelial ETB receptors, the formation of nitric oxide (NO) is stimulated. In the absence of smooth muscle endothelin receptor stimulation, this NO causes vasodilation." (From cvphysiology.com)
 
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