Question regarding umbilical cord stem cells

[predentchick]

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Hey there MD's! My husband has retinitis pigmentosa. He is looking into some therapy via umbilical cord stem cells. The procedure is done in England. They inject him with the cord's WBC and hopefully they go to his damaged eyes. (But you know this). My question is, what are the drawbacks and can this effect our children? I have had these questions answered but I am looking for as many opinions as possible. Thanks for your time!

 

[aphistis]

You might consider posting this in the ophthalmology forum, if you haven't already.

 

[predentchick]

Will do! Thx.

 

[predentchick]

Please respond if you know anything about this! I would help a lot. Thanks!

 

[v-tach]

As for your question about "can this affect our children", RP does seem to be a genetic problem. Therefore, there is the possibility of passing it on to offspring. However, I am not sure if the allele is dominant or recessive--could somebody shed a little light on that?

 

[closertofine]

As for your question about "can this affect our children", RP does seem to be a genetic problem. Therefore, there is the possibility of passing it on to offspring. However, I am not sure if the allele is dominant or recessive--could somebody shed a little light on that?

I wasn't sure either, and I was curious...so I looked it up, and apparently there are 3 different possible inheritance patterns. They were described briefly on the following website, and a few other sites I looked up said something similar:

http://www.visionchannel.net/retinitis/

 

[predentchick]

I know that the RP is genetic and can effect our kids. There are many ways it can be inherited. (autosomal recessive is what my husband got) I meant can the stem cell therapy effect his sperm cells/problems in children. Sorry for not clarifying.