quick histo question

[Little Soldier]

does anybody here know how to tell the difference between smooth muscle and dense (regular) connective tissue? occasionally striated muscle falls into this equation aswel when they are arranged obliquely on the slide. this is referring only to H&E stain. ive been having trouble with this for weeks, any advice would be awesome. Please dont say practice, because practice is only effective when youre doing it right and if i dont know which is which then i definitely am not, conversely searching through the internet for examples only yields the most obvious examples of each and this doesnt translate into looking at the slides my uni gives me.

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[Packman2003]

does anybody here know how to tell the difference between smooth muscle and dense (regular) connective tissue? occasionally striated muscle falls into this equation aswel when they are arranged obliquely on the slide. this is referring only to H&E stain. ive been having trouble with this for weeks, any advice would be awesome. Please dont say practice, because practice is only effective when youre doing it right and if i dont know which is which then i definitely am not, conversely searching through the internet for examples only yields the most obvious examples of each and this doesnt translate into looking at the slides my uni gives me.

Nuclei in smooth muscle

 

[alamo4]

Nuclei in smooth muscle

This

Actually, although that is true, it can be sometimes a bit confusing if there are a lot of fibroblasts mixed in with type I collagen.

There are some good tips here:

http://www.bu.edu/histology/m/append04.htm

 

[Little Soldier]

thanks so much bud, this is fantastic. love this site

 

[BlaseFaire]

Yeah, that site is the best for distinguishing between cell types people typically have trouble with.