This is on page 1 of the academic rad onc manual I thought.
But if RT helps .... DJT wasn't 100% wrong
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This is on page 1 of the academic rad onc manual I thought.
But if RT helps .... DJT wasn't 100% wrong
If you would have told me DT would someday advance my health and career and save millions of lives... yea, we’ll just leave it at that for now.
A moment of silence for deleted1002574
The artist formerly known as @ROFallingDown, this thread's starter.
It's an unwieldy, ugly, beautiful, sensationalistic, informative, 7-headed Hydra of a thread that will go on ad infinitum in perpetuity ad nauseum.
Unofficially, and now officially?, SDN Rad Onc's greatest thread of all time.
RIP ROFallingDown
The artist formerly known as @ROFallingDown, this thread's starter.
It's an unwieldy, ugly, beautiful, sensationalistic, informative, 7-headed Hydra of a thread that will go on ad infinitum in perpetuity ad nauseum.
Unofficially, and now officially?, SDN Rad Onc's greatest thread of all time.
RIP ROFallingDown
ROFD deleted his account?
Guy was forced out by the right wing media
When Trump fires Fauci to be replaced with Mohammad Khan. There will be two rad oncs at the top, people are saying. Trump will not be able to call him “Mohammad” so it will be “mo” and “steve” up there.
Mo money mo problems?
Another inside job by Evilbooya?
We’re going to know if it works from a single arm 5 patient study? What can possible be concluded from this? What a waste of resources and placing staff at risk.
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I don't think that it's such an absurd idea but holy crap does his tweet show a lack of self awareness. He just comes across as a snake oil salesman saying things like this trial "promises to improve patient outcomes" and "i suspect that this will be a game changer." He deserved every bit of the roasting that he got. Not because of the trial itself (I haven't read the protocol and don't care to) but because of the way he tried to sell it.
Tweets like these are how vaccines cause autism.
Tweets like these are how vaccines cause autism.
Same thing happening with Gilead right now. Lots of positive press without data.
That quote has to be taken in context with the rest of my statement. I offer very little support to what he’s doing but I don’t think he’s wrong for trying something out. “If” it works out, could be a great thing. I doubt it but I def am not in a position to know any better.
That’s fair! I’m just trying to wrap my head around what can possibly be learned from radiating the lungs of 5 critically ill covid pts? Even if none progress to MV have no way of knowing if the intervention did anything. If they all die do we conclude the intervention is not safe? I know people are desperate for treatments but....
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This sealed the deal imo
Attachments
Dr. Anthony Fauci says Gilead's remdesivir will set a new 'standard of care' for coronavirus treatment
Speaking to reporters, Fauci says he was told data from the trial showed a "clear-cut positive effect in diminishing time to recover."
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Dr. Anthony Fauci says Gilead's remdesivir will set a new 'standard of care' for coronavirus treatment
Speaking to reporters, Fauci says he was told data from the trial showed a "clear-cut positive effect in diminishing time to recover."www.cnbc.com
This really only benefits He propaganda wing and the traders looking for a quick buck.
Agree this is the one where I realized that the fellow has something going on supratentorially
Would like to see the data. Chinese study in Lancet was negative. Is this the beginning of the modern day "Space Race" with CHina playing the part of USSR. Propaganda awaited.Dr. Anthony Fauci says Gilead's remdesivir will set a new 'standard of care' for coronavirus treatment
Speaking to reporters, Fauci says he was told data from the trial showed a "clear-cut positive effect in diminishing time to recover."
the way things are looking we’ll all have to learn Mandarin quite soon.
I think the idea is that it is attenuating the virus and slowing down replication? People are looking for anything at this point...
Nope, nothing to do with me. Can't speak to ROFD's reasons of self-deleting his account.
maybe RO would be in a slightly better place if our own people believed in the GAME CHANGER goodness of our own modality rather than no radiation always being better. Some of the most anti XRT people i have met are actually fellow rad oncs. Tells you something about where we are today
How many people are fine with giving 5 years of AI therapy but squawk over 3 weeks of xrt? Just one of many examples...
This one probably drives me nuts the most. I have lost count of the number of people who have discontinued their AI due to arthralgias but made it through radiation without batting an eye. I'm not sure I can even remember a single patient that couldn't complete their course of adjuvant RT.
how many people? not that many.
the benefit of these 5 fraction courses are that a lot of people are basically treating everyone know. low grade DCIS or old breast cancer patient? observation versus 5 weeks of RT was a question. Now that it's 5 fractions, no reason to equivocate.
also don't know your experience, but you seem to bring this up a TON - did you train with breast rad oncs who were into observation? most don't.
if you're not getting the consults at all in the first place, that's a different story, and is something you should hash out with your referrings. In my experience, breast surgeons LOVE short course 5 fraction RT for their old ladies.
I'm talking about med oncs mainly these days. Get with the program and try living in the real world. Definitely some rad oncs out there that think that way also, however and, I'm not the only one who has seen that, clearly
almost said breast surgeons and med oncs. same thing. they both love the shorter courses. it's a much easier proposition to treat everyone when the courses and fields are smaller.
sorry that you don't have a good relationship with your referrings.
gotta grind man.
feel bad for you.
I get referrals from breast surgeons who get it. Obviously it's not foolproof and things are the way they are if patients filter through MO.
The bottom line is that our own specialty should advocate for xrt more in that argument and clearly many don't see that
Again, that is my point. I don't think breast rad oncs are advocating against RT. Literally there was stuff on social media yesterday about treating with RT alone instead of hormonal therapy alone from academic breast rad oncs.
I think you just like to believe that people are out to get you.
As a PP rad onc, I used the shorter courses as a way to get more patients than I ever treated before.
I would agree that its not really common if you have a good relationship in the community. Its only happened to me once in my short career. At tumor board the Med Onc said "Well she's 70 and its an early stage, small tumor so her benefit from RT is small. She still wanted to go through with it but when I explained to her all that was entailed... she agreed she didn't need it. The risk is low without RT.... right Dr. dieABRdie?"
I calmly explained "Yes... the risk is low... unless she discontinues her hormonal therapy. Then the risk is unacceptable. If she wants the lowest risk possible she should probably at least be offered it."
I saw her next week.
Good call!
I’ve started being more aggressive these days and letting the docs know where the data stands. I came into a practice that had limited referrals so I figured sucking up wasn’t going to make a difference in the rest of the community. If anything, there is a feeling of relief which I wish I would have started doing sooner. All of my older established partners didn’t care what was said about radiation and what it does.
Bottom line, we need to do more in our field and not focus on how we have to get referrals.
i don’t understand why the options are hormone therapy with or without radiation in these patients rather than hormone therapy OR radiation. If your options are 5-10 years of a pill with 33% compliance and pretty bad side effects that are often undersold Vs. 1 or 3 or even 5 weeks of radiation it seems like a no brainer...
The argument is that there is at least SOME systemic risk in low risk invasive patients. Systemic failure is what will kill a 70+ year old from breast cancer, not in breast recurrence. Antiestrogen therapy is a systemic treatment. Radiation is not.
Maybe, just maybe, we should be a little more intellectually honest and 1) admit that there is a real data-driven push not to give RT to the "old ladies" and 2) pushing for RT where 5-fx is a "reasonable option" in old ladies may itself constitute a shady practice. Maybe not shady in our arena, but others outside our arena may view it as shady. Up to and including OIG types. You think I kid; it's entirely possible OIG could see ubiquitous ("a lot of people are basically treating everyone now") RT for Stage I ER+ br CA patients as an overreach. And if OIG may not see it that way, CMS might; if the right one don't get you then the left one will. Full disclosure: yes sometimes I give the RT to the old ladies. But like Marvell said "At my back I always hear time's winged chariot hurrying near."
PRIME II and the Omission of Radiation Therapy in Low-Risk, Elderly Patients Undergoing Breast Conservation: The Time Has Come
Yes scarb - I agree that if we are being intellectually honest, RT reducting a 10-year risk of LR from 10% to 2% in CALGB trial definitely raises the question of 'why radiate for 8% improvment in LC when LC is likely not that important in this population of old ladies'? Non-rad oncs DEF have a point if they raise this question
However, when the argument shifts to "I can treat you 5 times to a small part of the breast' (my preference in my practice), the 'cost' to the patient in terms of time and toxicity becomes so low that the cost benefit ratio makes a lot more sense to just treat?
However, when the argument shifts to "I can treat you 5 times to a small part of the breast' (my preference in my practice), the 'cost' to the patient in terms of time and toxicity becomes so low that the cost benefit ratio makes a lot more sense to just treat?
It's a reasonable argument. However I have seen many reasonable arguments get kicked to the curb in my day!
I just worry that if it's presented as HT vs RT, the med oncs might get defensive/territorial if no one chooses HT.
yes.
and also, systemic therapy serves a different purpose, and if it's 'hormonal therapy until they can't tolerate it' as well as easy radiation, thats a pretty good approach for most early stage patients IMO
Is anybody noticing an increase of these “survey” requests. Will only take 15 min thanks. One one side i want to support a fellow resident getting a pub, but it seems more of this “research” is being done. What are your thoughts, beehive?
I would take the survey, if they could guarantee no pub in a medical journal, but ASTRO blog post, Twitter, or SDN is ok.
Being displayed in a major publication, gives this "research" unnecessary prestige. It should not pass review in my opinion.
Being displayed in a major publication, gives this "research" unnecessary prestige. It should not pass review in my opinion.
It's just getting worse and worse. With the internet and centralized databases of everyone's information, it takes very little effort to churn out this "research". Not just a RadOnc problem, it's a Medicine problem. As everyone "learns the game" people start working on their CVs earlier and earlier and to an increasing degree. Look at your average medical school applicant now vs 20 years ago. It's ridiculous. With most programs adapting to the mandatory 4th year of residency in the late 90s by turning it into a research year, RadOnc just got (and maintained) a head start on the rest of the gang.
ya but most of them is clearly for a pub. You get all the data do a quick write up boom!
is this “the game” now?
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I received 2 surveys this year, which is down from in the past IMO thankfully lol
1) Minnesota on COVID impact on rad onc
2) ARRO survey on each program
ARRO survey is fine, IMO. I see this as a QA exercise for an organization that is advocating for residents. They have had a track record of advocating, particularly in the physics/radbio fiasco. I will be happy to spend as much time necessarily to give them the data they need.
The Minnesota resident survey on COVID impact is frankly shameful. Such research does nothing to improve patient outcomes, nor does it improve our field in any way. But it will be a Red Journal publication in a few months and a line in this resident's CV, sigh. Sent immediately to my spam box
not exactly a “happening place.” Familiar with program. To put it into context, look up GFunk’s review of the place from when he was applying to residency. The same review applied a few years ago. Doubt it has changed.
