"Alerting men and #WomenwhoCurie from Oceania" is *chef kiss*
I think the days of hungry new grads going to upper Midwest for amazing salaries are done. The salaries are not amazing anymore and even the new grads don't want to tolerate living in those places for a few years. Maybe in the near future when they're having trouble getting A job but the money won't be there.
I agree! But, yes you are preaching to the choir… I’ll see you again on Sunday!I know I'm preaching to the choir on this forum, but at least this way it will show up in a Google search:
For those of us who treat breast with any regularity, we can tell you that in 2022 (and beyond), radiation is an absolute breeze compared to FIVE YEARS of endocrine therapy. It's not even in the same universe.
If society is going to push for omission of one of the three components of breast-conserving therapy, it's a medicine you need to take for FIVE YEARS, not the treatment which, at worst, takes 3 weeks (15 treatments), can can often be done quicker (5 treatments).
I apologize in advance for how many times I repeat myself in the coming years.
It's going to be absolute no-brainer argument if I can consult the breast patient at 9 am, sim at 10, and complete the entire course of post-lumpectomy EBRT by noon.I know I'm preaching to the choir on this forum, but at least this way it will show up in a Google search:
For those of us who treat breast with any regularity, we can tell you that in 2022 (and beyond), radiation is an absolute breeze compared to FIVE YEARS of endocrine therapy. It's not even in the same universe.
If society is going to push for omission of one of the three components of breast-conserving therapy, it's a medicine you need to take for FIVE YEARS, not the treatment which, at worst, takes 3 weeks (15 treatments), can can often be done quicker (5 treatments).
I apologize in advance for how many times I repeat myself in the coming years.
I know I'm preaching to the choir on this forum, but at least this way it will show up in a Google search:
For those of us who treat breast with any regularity, we can tell you that in 2022 (and beyond), radiation is an absolute breeze compared to FIVE YEARS of endocrine therapy. It's not even in the same universe.
If society is going to push for omission of one of the three components of breast-conserving therapy, it's a medicine you need to take for FIVE YEARS, not the treatment which, at worst, takes 3 weeks (15 treatments), can can often be done quicker (5 treatments).
I apologize in advance for how many times I repeat myself in the coming years.
I know I'm preaching to the choir on this forum, but at least this way it will show up in a Google search:
For those of us who treat breast with any regularity, we can tell you that in 2022 (and beyond), radiation is an absolute breeze compared to FIVE YEARS of endocrine therapy. It's not even in the same universe.
If society is going to push for omission of one of the three components of breast-conserving therapy, it's a medicine you need to take for FIVE YEARS, not the treatment which, at worst, takes 3 weeks (15 treatments), can can often be done quicker (5 treatments).
I apologize in advance for how many times I repeat myself in the coming years.
I strongly suspect this is the case, spending as much time as I did in academia vs now in general practice.YES!
Especially those I see after 5 fraction Livi.
We spend our time talking about AI side effects, not breast issues. Chasing hot flashes with SSRI's/gabapentin, adding more meds (Prolia) to strengthen bone, my joints hurt, etc.
It makes me think any rad onc running these omission trials does not have a busy breast clinic or does not see patients in follow up after a year on their AI. Seems impossible that would be the case but who knows?!?
I think there would be close to 💯 % agreement among radoncs. To me, the real issue is the outrageous residency expansion in light of these entirely predictable developments in the face of multiple warnings on social media and in the red journal by the likes of shah and zeitman. Scarop still feels that sdn is a hotbed of unjustified concerns.I know I'm preaching to the choir on this forum, but at least this way it will show up in a Google search:
For those of us who treat breast with any regularity, we can tell you that in 2022 (and beyond), radiation is an absolute breeze compared to FIVE YEARS of endocrine therapy. It's not even in the same universe.
If society is going to push for omission of one of the three components of breast-conserving therapy, it's a medicine you need to take for FIVE YEARS, not the treatment which, at worst, takes 3 weeks (15 treatments), can can often be done quicker (5 treatments).
I apologize in advance for how many times I repeat myself in the coming years.
Oh good, they included ipi.
A reason to concerned about MSI status in rectal in the short term. Short course XRT with dual immunotherapy. Not sure if this protocol would be adjusted based on MSKCC data.
Can be opened in community places through NCORP.
Oh good, they included ipi.
I am going to make a counterpoint here.I know I'm preaching to the choir on this forum, but at least this way it will show up in a Google search:
For those of us who treat breast with any regularity, we can tell you that in 2022 (and beyond), radiation is an absolute breeze compared to FIVE YEARS of endocrine therapy. It's not even in the same universe.
If society is going to push for omission of one of the three components of breast-conserving therapy, it's a medicine you need to take for FIVE YEARS, not the treatment which, at worst, takes 3 weeks (15 treatments), can can often be done quicker (5 treatments).
I apologize in advance for how many times I repeat myself in the coming years.
Obviously a cure is hyperbole, but there is a steady march of progress w/each asco and that is certainly an existential threat to our job market. Radiation wont disappear but its footprint will be much smaller by asco 2030. I can see with better chemo/io combos and newer IO agents in the following scenarios. oustide ctla4 and PDL1, not many other immuno targets, but they will come!
In the properly selected population omitting RT hurts in breast recurrences without affecting survival. (PRIME-II etc.) In fact I guess in these types trials of all the outcomes reported it’s always OSs (vs recurrence or mets eg) that have smallest delta between RT and no RT. It thus certainly may be possible that omitting anti-E therapy will see no difference in local controls but worse OS. That would be… infaust.I am going to make a counterpoint here.
Although I fully agree that radiation is a lot more comfortable and less toxic than 5 (-10) years of antihormonal treatment, it‘s not so easy to state „If you are going to drop something, drop the antihormonal treatment.“
You need to:
A) Do the trials to prove that.
B) Bear in mind that RT and AHT have different effects. RT merely influences in-breast recurrence risk (and with PBI only in a part of that breast), while AHT also tackles DCIS in the contralateral breast as well as lowers the risk for regional/distant recurrence. Communication of these distinct goals is not that trivial and quantification of the associated benefits with each treatment still not well (because we have not done the proper trials) understood.
Many patients are not concerned about a local recurrence but rather systemic relapse or a second primary. These needs of the patients must be weighted carefully when thinking about how to deescalate treatment.
We still have a lot of work to do!
Totally agree - which is why I save the hyperbolic statements in this arena for my SDN avatar.I am going to make a counterpoint here.
Although I fully agree that radiation is a lot more comfortable and less toxic than 5 (-10) years of antihormonal treatment, it‘s not so easy to state „If you are going to drop something, drop the antihormonal treatment.“
You need to:
A) Do the trials to prove that.
B) Bear in mind that RT and AHT have different effects. RT merely influences in-breast recurrence risk (and with PBI only in a part of that breast), while AHT also tackles DCIS in the contralateral breast as well as lowers the risk for regional/distant recurrence. Communication of these distinct goals is not that trivial and quantification of the associated benefits with each treatment still not well (because we have not done the proper trials) understood.
Many patients are not concerned about a local recurrence but rather systemic relapse or a second primary. These needs of the patients must be weighted carefully when thinking about how to deescalate treatment.
We still have a lot of work to do!
Unfortunately this is sad, but true. I think we are so dependent on technology that our next real advance will be based on some future technological advance that makes radiation dose-esc quicker, faster, more effective, and safer.Obviously a cure is hyperbole, but there is a steady march of progress w/each asco and that is certainly an existential threat to our job market. Radiation wont disappear but its footprint will be much smaller by asco 2030. I can see with better chemo/io combos and newer IO agents in the following scenarios. oustide ctla4 and PDL1, not many other immuno targets, but they will come!
chemo/io-> surgery for esophagus
2nd/3rd generation Chemo/io regimens as neoadjuvant treatment of choice in majority of stage III lung.
IO cutting down on brain met pts getting srt.
chemo/IO-if followed by a very good response- leading to a less radical surgery (wedge, in lung) simple hysterectomy in cervix, TURB in bladder.
i think he’s saying the end of equivocation over whether one should resect or irradiate IIIB for any IIIB patient who even seems to have a toe in the potentially resectable poolThe end of what?
i think he’s saying the end of equivocation over whether one should resect or irradiate IIIB for any IIIB patient who even seems to have a toe in the potentially resectable pool
our own personal Jesus. What will
Save the specialty?
our own personal Jesus. What will
Save the specialty?
Grid has been around since the 1950s. Was originally used in Manchester with orthovoltagw to treat deeper tumors but spare skin.Grid, lol. That been around since at least the 1990’s but ya that’s where we are going to find meaningful innovation.
our own personal Jesus. What will
Save the specialty?
curious about this? my community shop exclusively does HA-WBRT for patients who can wait 2-3 days to start. are other PP docs not doing this? it's also better billing....
Radiopharm won’t support the specialty. Nuc med/radiology controls it in large systems and let’s face it, the sht reimbursement of this loss leader won’t be able to keep radoncs employed
And the lutetium is a real pain btw. Get same rvus for 2-3 cbctEnjoy your 79101 with 1.96 wRVU per administration. I'm sure that will make up for all those fractions lost.
Real time suck, and a financial risk if you're buying the drug and the billers don't know what they are doingAnd the lutetium is a real pain btw. Get same rvus for 2-3 cbct
And the lutetium is a real pain btw. Get same rvus for 2-3 cbct
Real time suck, and a financial risk if you're buying the drug and the billers don't know what they are doing
curious about this? my community shop exclusively does HA-WBRT for patients who can wait 2-3 days to start. are other PP docs not doing this? it's also better billing....