I applied for 2007 and didn't get any interest from schools. Re applied June 2007 for 2008, retook the mcat in July, and did several points better than the first time. Went from 1 interview in the first cycle to 6 interviews in the second, 3 of which I canceled because I had already gotten accepted at my top two schools. I had hardly any new activities because I didn't find out I didn't make it until late spring of 2007, but it really seemed to be about numbers at most schools. My essay was pretty much the same both cycles, just made minor changes, and didn't mention the reapplication. There really is hope, although it seemed like such a smack in the face, it was a blessing in disguise for me. In my year off I have grown so much and am ready continue my education.
You should make sure your mcat is where it needs to be and apply to the right schools for you.