Can someone explain RI to me? I read >2% = hemolysis <2%= underproduction. So does that mean that an appropriate bone marrow response is exactly 2??
-Thanks for the help, Joe
-Thanks for the help, Joe
-
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Reticulocyte Index?
Started by TennisProJoe
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Moving to Clinical Rotations.
in a normal person wiht hgb 12-15, it should be around 1%. If you are anemic, you lose normal red cells, so it naturally goes up from basic mathemticas perspective. hgb of 8 has like 2% retic if nothing else changes.
Now when you're anemic, your body decides to increase the rate of red cell production and shoot em out early. Therefore, with that hgb of 8 and retic of 2%, your body is failing to increase production appropriately. if your retic count is 4% in this case then your body is doing the appropriate compensation. If your retic count is less than 2%, your body is really failing to compensate.
Either way you hve to look at the overall clinical picture. a specific retic % is a clue to whether your body is underproducing, unable to increase production, or is able to appropriately compensate. But it does not tell you specifically what process is causing the anemia.
Now when you're anemic, your body decides to increase the rate of red cell production and shoot em out early. Therefore, with that hgb of 8 and retic of 2%, your body is failing to increase production appropriately. if your retic count is 4% in this case then your body is doing the appropriate compensation. If your retic count is less than 2%, your body is really failing to compensate.
Either way you hve to look at the overall clinical picture. a specific retic % is a clue to whether your body is underproducing, unable to increase production, or is able to appropriately compensate. But it does not tell you specifically what process is causing the anemia.
