MudPhud20XX Full Member 10+ Year Member Jan 30, 2016 #1 Advertisement - Members don't see this ad FA says Rituximab can be used for ITP (Immune Thrombocytopenic Purpura), any thoughts about the mech?
Advertisement - Members don't see this ad FA says Rituximab can be used for ITP (Immune Thrombocytopenic Purpura), any thoughts about the mech?
S stop2stop Full Member 7+ Year Member Jan 30, 2016 #2 It's an immune disorder. Rituximab takes out B cells, thus knocking down the immune system. Simplified, but that's why we use it for a number of autoimmune things Upvote 0 Downvote
It's an immune disorder. Rituximab takes out B cells, thus knocking down the immune system. Simplified, but that's why we use it for a number of autoimmune things
Jabbed Full Member 10+ Year Member Jan 30, 2016 #3 Primary defect in ITP is the production of anti-GpIIbIIIa antibodies. Rituximab inhibits B cells / plasma cells and decreases antibody production. Upvote 0 Downvote
Primary defect in ITP is the production of anti-GpIIbIIIa antibodies. Rituximab inhibits B cells / plasma cells and decreases antibody production.