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So apparently the people who run RxPrep won't help me solve questions from the RxPrep book. Would anyone care to help me?
On page 137, Ch. 7 Pharmacokinetics, Question 1:
Patient getting ciprofloxacin 400 mg IV Q12H. Convert IV to PO when the bioavailablity of Cipro is 70%. Pharmacy has the following tablets available: 250, 500, and 750 mg strengths.
a) 250 mg PO dialy
b) 250 mg PO BID
c) 500 mg PO BID
d) 750 mg PO BID
e) 250 mg PO Q8H
The right answer seems to be c. When I did the question I got 1360 mg of ciprofloxacin in a day (I multiplied the total daily dose by 70% and added that amount to the daily dose). I would think the answer would be d) 750 mg PO BID instead of c) 500 mg PO BID because It's closer to the value I got.
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One that same page (p. 137), Question 5. How would I determine how to solve that question:
Pt was getting phenytoin 300 mg PO HS for one month. Plasma sample is 10 mg/L. Goal is 15 mg/L, which recommendation is appropriate?
a) increase dose to 450 mg hs
b) incr to 330 mg PO hs
c) incr to 500 mg hs
d) reduce to 250 mg hs
e) continue current dose
Answer: b, I have no idea how to solve it though
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On page 178 (Ch. 10: Biostats), Question 3.
Calculate relative risk reduction of experiencing primary endpoint. Primary endpoint occurred in 12.1% of clopidogrel group and 9.9% of prasugrel group. Study wanted to compare prasugrel to Plavix.
a) 81.8%
b) 50%
c) 18.2 %
d) 122%
e) 69%
I solved the question by doing this: (12.1% - 9.9%)/12.1% = 0.18%, which is not an answer choice. It says on there that the answer is c) 18.2%, however the numbers are already percentages in the problem so multiplying the answer by 100% wouldn't make sense.
On page 137, Ch. 7 Pharmacokinetics, Question 1:
Patient getting ciprofloxacin 400 mg IV Q12H. Convert IV to PO when the bioavailablity of Cipro is 70%. Pharmacy has the following tablets available: 250, 500, and 750 mg strengths.
a) 250 mg PO dialy
b) 250 mg PO BID
c) 500 mg PO BID
d) 750 mg PO BID
e) 250 mg PO Q8H
The right answer seems to be c. When I did the question I got 1360 mg of ciprofloxacin in a day (I multiplied the total daily dose by 70% and added that amount to the daily dose). I would think the answer would be d) 750 mg PO BID instead of c) 500 mg PO BID because It's closer to the value I got.
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One that same page (p. 137), Question 5. How would I determine how to solve that question:
Pt was getting phenytoin 300 mg PO HS for one month. Plasma sample is 10 mg/L. Goal is 15 mg/L, which recommendation is appropriate?
a) increase dose to 450 mg hs
b) incr to 330 mg PO hs
c) incr to 500 mg hs
d) reduce to 250 mg hs
e) continue current dose
Answer: b, I have no idea how to solve it though
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On page 178 (Ch. 10: Biostats), Question 3.
Calculate relative risk reduction of experiencing primary endpoint. Primary endpoint occurred in 12.1% of clopidogrel group and 9.9% of prasugrel group. Study wanted to compare prasugrel to Plavix.
a) 81.8%
b) 50%
c) 18.2 %
d) 122%
e) 69%
I solved the question by doing this: (12.1% - 9.9%)/12.1% = 0.18%, which is not an answer choice. It says on there that the answer is c) 18.2%, however the numbers are already percentages in the problem so multiplying the answer by 100% wouldn't make sense.
