I think some schools don't like it when you take classes the summer right before matriculation - meaning don't wait to take organic until Summer 09 if you want to enter pharm school Fall 09. Other than that, I doubt it matters much. But I took organic I over the summer and it was *hard*. It's a lot of information to cram into 4-6 weeks and I would never recommend it. Take just the lab portion or just the lecture portion if you must - doing both was really difficult and I don't think I absorbed the material as well.