Section bank #81 ambiguity

[salemstein]

---

Members don't see this ad.

Wouldn't you get glucose from AcetylCoA as well, because if it goes into the CAC, you end up with OAA at some point (which feed directly into the gluconeogenesis)?

 

[Mr. otcoD]

View attachment 204415

Wouldn't you get glucose from AcetylCoA as well, because if it goes into the CAC, you end up with OAA at some point (which feed directly into the gluconeogenesis)?

Technically yes you would be able to get OAA from that. But the question is asking for precursors for gluconeogensis. So you don't want to be dealing with glycolysis+TCA+OxPhos that much because you're trying to increase glucose levels in the cell. IMO, i wouldnt have put Acetyl-CoA based on that. Its easier to lose Carbons to get the precursor vs adding carbons to get the precursor (which is why alpha-keto is ok)

 

[theonlytycrane]

For acetyl-coa to go into the TCA, you need to use oxaloacetate. Oxaloacetate is regenerated at the end, but the net gain of oxaloacetate is 0. Acetyl-coa isn't "turned into" oxaloacetate.