Step II Sickle cell complications

[The kitchen sink]

In these 2 sickle cell complications:

Aplastic crisis - decreased Hg and very low retic count

Splenic Sequestration - decreased Hg with appropriate retic count

I read in a source that you can differentiate these 2 conditions by looking at platelet count, it says that platelet count is decreased in Aplastic crisis, and normal or increased platelets in splenic sequestration.

Im not sure if its getting confused with aplastic anemia, where you would see pancytopenia, but in aplastic crisis I thought there was only an arrest of erythropoesis due to a Parvovirus b19 infection or something

Can someone tell if this is true or not because in the qbank, the patient presenting with the aplastic crisis had a normal platelet count.

thanks

 

[cbcb00]

Your source appears to be wrong. During aplastic crisis, parvo only affects rbc precursors and doesn't do anything to the platelets. In aplastic anemia, the bone marrow as a whole doesn't function, so you get a decrease in all cell lines..... Aka qbank is right 🙂

 

[The kitchen sink]

Your source appears to be wrong. During aplastic crisis, parvo only affects rbc precursors and doesn't do anything to the platelets. In aplastic anemia, the bone marrow as a whole doesn't function, so you get a decrease in all cell lines..... Aka qbank is right 🙂

thanks for the clarification

 

[Transposony]

Doesn't the retic count differentiate the two?

 

[Ronin786]

Doesn't the retic count differentiate the two?

Yup. Its the retics thats going to solve the question.