Singulair for dogs

[sammy15]

does anyone know of any long term effects of a singulair overdose in dogs? I cannot find good information anywhere. Thank you.

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[Angelo84]

I'm going to assume your looking at this for school and not seeking medical advice for a personal pet. Have you looked at Plumb's veterinary drug handbook? It might not have singular as its a human drug but that's a good place to check. If that doesn't work try the animal poison control hotline. Or ask a local vet if you know of one.

 

[BrumleyVet]

If you are a Pharmacy student, why are you asking about the effect a med has on a dog?

 

[sammy15]

Not for my dog. Long story but it came up in discussion I was having with a friend about singulair being used in dogs for asthma/allergy treatment? (I did read some info about this) I thought it was interesting as I like pharmacy and animals (and wish there was such a job as a veterinary pharmacist). Anyhow there's not much info on human OD either. (by the way I'm not technically a pharmacy student for 2 more days so I don't know much) I was just wondering if anyone had experience with it.

 

[pressmom]

From rxlist:

http://www.rxlist.com/cgi/generic/monteluk_od.htm

No mortality occurred following single oral doses of montelukast up to 5000 mg/kg in mice (estimated exposure was approximately 335 and 210 times the AUC for adults and children, respectively, at the maximum recommended daily oral dose) and rats (estimated exposure was approximately 230 and 145 times the AUC for adults and children, respectively, at the maximum recommended daily oral dose).
No specific information is available on the treatment of overdosage with SINGULAIR. In chronic asthma studies, montelukast has been administered at doses up to 200 mg/day to adult patients for 22 weeks and, in short-term studies, up to 900 mg/day to patients for approximately a week without clinically important adverse experiences. In the event of overdose, it is reasonable to employ the usual supportive measures; e.g., remove unabsorbed material from the gastrointestinal tract, employ clinical monitoring, and institute supportive therapy, if required.
There have been reports of acute overdosage in post-marketing experience and clinical studies with SINGULAIR. These include reports in adults and children with a dose as high as 1000 mg. The clinical and laboratory findings observed were consistent with the safety profile in adults and pediatric patients. There were no adverse experiences in the majority of overdosage reports. The most frequently occurring adverse experiences were consistent with the safety profile of SINGULAIR and included abdominal pain, somnolence, thirst, headache, vomiting and psychomotor hyperactivity.
It is not known whether montelukast is removed by peritoneal dialysis or hemodialysis.

 

[chris03333]

Not for my dog. Long story but it came up in discussion I was having with a friend about singulair being used in dogs for asthma/allergy treatment? (I did read some info about this) I thought it was interesting as I like pharmacy and animals (and wish there was such a job as a veterinary pharmacist). Anyhow there's not much info on human OD either. (by the way I'm not technically a pharmacy student for 2 more days so I don't know much) I was just wondering if anyone had experience with it.

With an acute ingestion of leukotriene inhibitor, generally you see GI upset...But I can not comment on "long term effects". Read up on leukotriene inhibitors for your human info.

 

[david594]

Not for my dog. Long story but it came up in discussion I was having with a friend about singulair being used in dogs for asthma/allergy treatment? (I did read some info about this) I thought it was interesting as I like pharmacy and animals (and wish there was such a job as a veterinary pharmacist). Anyhow there's not much info on human OD either. (by the way I'm not technically a pharmacy student for 2 more days so I don't know much) I was just wondering if anyone had experience with it.

I'm pretty sure my local vet school teaching hospital had an opening for a pharmacist.


Go here: https://recruiter.kenexa.com/tufts/cc/CCJobSearchAction.ss?command=CCSearchPage&ccid=bupJEdUjsTs=

And search for this number: 11170 https://recruiter.kenexa.com/tufts/...d=ViewJobDetails&job_REQUISITION_NUMBER=11170

 

[sammy15]

I'm pretty sure my local vet school teaching hospital had an opening for a pharmacist.


Go here: https://recruiter.kenexa.com/tufts/cc/CCJobSearchAction.ss?command=CCSearchPage&ccid=bupJEdUjsTs=

And search for this number: 11170 https://recruiter.kenexa.com/tufts/...d=ViewJobDetails&job_REQUISITION_NUMBER=11170

nice! thank you. thanks everyone else also for your info.

 

[inmyownright]

Pharmacists actually learn about drugs period, doesnt matter whether they are human or animal. In fact, they need to know about the effects on animals in case they choose to go into pharmaceutical research. There is such thing as a veterinary pharmacists see http://www.vetmeds.org/. I am a pharmacist of 14 years standing currently at vet school, and despite the ignorance of the poster asking why a pharmacist should want to know about veterinary medicines in dogs, I'm kicking ass in vet pharmacology.

 

[Aznfarmerboi]

Pharmacists actually learn about drugs period, doesnt matter whether they are human or animal. In fact, they need to know about the effects on animals in case they choose to go into pharmaceutical research. There is such thing as a veterinary pharmacists see http://www.vetmeds.org/. I am a pharmacist of 14 years standing currently at vet school, and despite the ignorance of the poster asking why a pharmacist should want to know about veterinary medicines in dogs, I'm kicking ass in vet pharmacology.

👍 and with cases concerning overdoses; a lot of toxicologists consulting in your poison control centers is a pharmacist. Not sure about animal poison control centers. I have never heard of one and am going to look into this as a future references for anybody who might need one.

 

[Bill59]

The National Animal Poison Control center is staffed by veterinary toxicologists.

 

[twelvetigers]

The ASPCA Animal Poison Control Center is at the University of Illinois. I think Truth74 (fellow pre-vet poster) works there.

 

[Truth74]

The ASPCA Animal Poison Control Center is at the University of Illinois. I think Truth74 (fellow pre-vet poster) works there.

Did somebody mention my name?

Hey there twelvetigers, I do work there, but we are not at the University of Illinois. The ASPCA Animal Poison Control Center is an affiliate partner with the University of Illinois, though.

The APCC was created by Dr. William Buck who was a Veterinary Toxicologist at the University of Illinois. It had graduate and vet students answering the phones during that time (30 years ago). When it grew too large to handle, the APCC was taken over by the ASPCA, and thus became a separate entity. Now, there are board certified veterinary toxicologists, veterinarians on their way to certification, CVT's, vet students, and veterinary assistants on staff at the call center 24hrs a day. I do not know if pharmacists ever worked at the APCC or will ever work there.

 

[twelvetigers]

SEE? I might have been wrong about the Illinois location, but I found the board expert on the matter. 😀

 

[Truth74]

Expert? Not so much. I just happen to have a little bit of information. Notice... I gave no advice what so ever. 🙂

 

[Kittenmommy]

Pharmacists actually learn about drugs period, doesnt matter whether they are human or animal. In fact, they need to know about the effects on animals in case they choose to go into pharmaceutical research.

Or in case they work at my local Target pharmacy, where I go to get Prednisone and Leukeran for my cat with intestinal lymphoma.

The pharmacists there are always on the ball, they always have the Leukeran in stock (despite it being a highly perishable drug that pharmacies don't generally stock - they stock it just for her) and they're always able to answer my questions. I have nothing but praise for that particular Target pharmacy! 😎