B birchswing Non-medical 10+ Year Member Joined Nov 17, 2011 Messages 1,953 Reaction score 911 Mar 30, 2014 #1 Members don't see this ad. Is there a chart somewhere that shows how each SSRI is metabolized? In particular, I'm curious if there is one that doesn't use Cytochrome P450 2D6.
Members don't see this ad. Is there a chart somewhere that shows how each SSRI is metabolized? In particular, I'm curious if there is one that doesn't use Cytochrome P450 2D6.
nitemagi Senior Member Verified Member Physician Faculty 15+ Year Member 20+ Year Member Joined Oct 16, 2001 Messages 2,871 Reaction score 1,009 Mar 30, 2014 #2 http://drug-interactions.com
shan564 Full Member 15+ Year Member Joined May 30, 2007 Messages 2,559 Reaction score 465 Mar 30, 2014 #3 Paroxetine and fluoxetine use 2D6 to a significant extent. Sertraline and (es)citalopram use little to none. The geriatric psychiatrists at my institution hate using fluoxetine or paroxetine for anything. Here's the result of a quick google search: http://www.preskorn.com/books/ssri_s6.html
Paroxetine and fluoxetine use 2D6 to a significant extent. Sertraline and (es)citalopram use little to none. The geriatric psychiatrists at my institution hate using fluoxetine or paroxetine for anything. Here's the result of a quick google search: http://www.preskorn.com/books/ssri_s6.html
Shikima Full Member Verified Member Physician 15+ Year Member Joined Oct 15, 2006 Messages 4,580 Reaction score 2,796 Mar 31, 2014 #4 But if that's all you have to work with due to unique biochemistry..
PikminOC MD Attending Physician Removed Verified Member 10+ Year Member Physician Joined Sep 12, 2010 Messages 6,101 Reaction score 3,104 Mar 31, 2014 #5 Brintellix has elderly indication