Rx questions are generally straightforward but people don't do super well partly because they usually haven't done much studying yet (M1s), and people often go through it quickly in tutor mode (I know I misclick a lot or don't read all the answers but can't change it). And since it just tests your First Aid knowledge, it feels pretty easy for people who just went through that FA chapter, and difficult for those who haven't.
Rx is good for going through with your organ blocks, especially if you use First Aid at all alongside your blocks. I don't think you HAVE to do 40 question blocks. I'd worry more about content for now, but it couldn't hurt.
I was just thinking about how I wished I did Sketchy Micro and Pharm alongside my organ blocks (but we integrated those into each block instead of having a micro or pharm course) and maybe Pathoma earlier to make sure I didn't miss any high-yield path - as most path lecturers we had were not great at highlighting important info.