In college, I kept a 3.99 as a non-science major, but at a very high cost. I studied 7 days a week, for much or most of each day. I would go to sleep between 6-8 am, and wake up for class about 10 on the days I had class. I would take 20 minute power naps on the floors of the cafeteria, in the library stacks, and at the back of the classroom while waiting for my next class to start. When exams came around, I would study 17 or 18 hours a day. I became very sick after most midterm and final periods.
I did have the luxury of knowing my grade before ever took the exam, but when it was all said and done, I think I learned less than people who studied less or got B's. I didn't allow myself to enjoy the subjects or immerse myself in them, and I almost feel like dong it all over again because they were all, for one reason or another, worthwhile.
Grades are important when it comes to post graduate work, no doubt. But keep it in perspective. Try very hard to maintain an interest in all your subjects. Focus on the main points first, and once you have a complete understanding of those main points, the details will adhere to them. For me, if I read something three times, I will know it well enough to get the A. Some people might need only one or two readings. Find out what works for you, but try not to highlight during your first reading. I spent a lot of time coloring my textbooks yellow. I should have just soaked them. Now I don't highlight at all. On my second reading, I put down post-it flags next to the key points. I only allow myself 20-30, so when they run out I quickly go back to the marked passages, skim them, and remove the flag. Whatever you do, strive to study efficiently, not excessively. Take a day off now and then, go for walks on your study breaks, and push yourself, but not too much. Always be your own advocate. Sorry for rambling ... Good luck to you.