So I see that nobody fully understands Sn1 E1 Sn2 E2
I have been trying to come up with general rules to memorize can sombody tell me if this right?
Methyl Halides (CH3X)
Sn2 Only
Primary Halides (RCH2X)
Sn2 if reacted with a good nucleophile.
E2 if reacted with a bulky base such as CH3CO-
No E1
No Sn1
Secondary Halides (R2CHX)
Sn2 with weak bases such as CN-, N3-, CH3COO-, SH-, RS-, I-.
E2 with strong bases such as OH- , CH3CH2O-, or NH2-
Sn1 and E1 with benzylic and allylic halides, weak bases and polar protic solvents
Tertiary Hailides (R3C-X)
Sn1 and E1 in hydroxylic solvents (Polar Protic Solvents)
---Solvolysis stablizes carbocation intermediate
---At higher temeratures E1 is favored
E2 is favored when bases are used
---No solvolysis
No Sn2 too crowded
I have been trying to come up with general rules to memorize can sombody tell me if this right?
Methyl Halides (CH3X)
Sn2 Only
Primary Halides (RCH2X)
Sn2 if reacted with a good nucleophile.
E2 if reacted with a bulky base such as CH3CO-
No E1
No Sn1
Secondary Halides (R2CHX)
Sn2 with weak bases such as CN-, N3-, CH3COO-, SH-, RS-, I-.
E2 with strong bases such as OH- , CH3CH2O-, or NH2-
Sn1 and E1 with benzylic and allylic halides, weak bases and polar protic solvents
Tertiary Hailides (R3C-X)
Sn1 and E1 in hydroxylic solvents (Polar Protic Solvents)
---Solvolysis stablizes carbocation intermediate
---At higher temeratures E1 is favored
E2 is favored when bases are used
---No solvolysis
No Sn2 too crowded
