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succinylcholine

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Phloston

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nAChR is a non-selective cation channel that releases lots of K+ (and Ca2+) when succinylcholine is administered.

Remember that nAChR are ionotropic (channels that open in response to ligand-binding) and mAChR are metabotropic (act via 2nd messengers).

I've seen in practice questions that nAChR are LIGAND-gated Na+/K+ channels (NOT Na/K-ATP-pumps), such that Na+ influxes AND K+ EFFLUXES when nAChR is activated.

Done deal.
 

jughead00

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nAChR is a non-selective cation channel that releases lots of K+ (and Ca2+) when succinylcholine is administered.

Remember that nAChR are ionotropic (channels that open in response to ligand-binding) and mAChR are metabotropic (act via 2nd messengers).

I've seen in practice questions that nAChR are LIGAND-gated Na+/K+ channels (NOT Na/K-ATP-pumps), such that Na+ influxes AND K+ EFFLUXES when nAChR is activated.

Done deal.

Wonderful!!! I got it. Thanks a lot :thumbup:
 
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