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This is what First Aid 2017 says about synthases and synthetases:
Combines 2 molecules into 1 (condensation reaction) either using an energy source (synthase, eg,
glycogen synthase) or not (synthetase, eg, PRPP synthetase).
I thought it was synthetases that require an energy source (ATP)?
This is from Wiki:
Note that, originally, biochemical nomenclature distinguished synthetases and synthases. Under the original definition, synthases do not use energy from nucleoside triphosphates (such as ATP, GTP, CTP, TTP, and UTP), whereas synthetases do use nucleoside triphosphates. However, the Joint Commission on Biochemical Nomenclature (JCBN) dictates that 'synthase' can be used with any enzyme that catalyzes synthesis (whether or not it uses nucleoside triphosphates), whereas 'synthetase' is to be used synonymously with 'ligase'
https://en.wikipedia.org/wiki/Synthase
Am I missing something or is there something wrong with FA or Wikipedia?
Combines 2 molecules into 1 (condensation reaction) either using an energy source (synthase, eg,
glycogen synthase) or not (synthetase, eg, PRPP synthetase).
I thought it was synthetases that require an energy source (ATP)?
This is from Wiki:
Note that, originally, biochemical nomenclature distinguished synthetases and synthases. Under the original definition, synthases do not use energy from nucleoside triphosphates (such as ATP, GTP, CTP, TTP, and UTP), whereas synthetases do use nucleoside triphosphates. However, the Joint Commission on Biochemical Nomenclature (JCBN) dictates that 'synthase' can be used with any enzyme that catalyzes synthesis (whether or not it uses nucleoside triphosphates), whereas 'synthetase' is to be used synonymously with 'ligase'
https://en.wikipedia.org/wiki/Synthase
Am I missing something or is there something wrong with FA or Wikipedia?