Step I tb treatment regimens

[daisygirl]

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Is one expected to know the treatment regimens for TB for step 1? Do I really have to know which combos are for six months, and which for nine months, and what ppd size-wise indicates treatment,.....

Please tell me no . The pharm section in first aid ignores stuff like this, so I'm hoping I can too 😀

 

[AlexRusso]

i'd say knowing that INH is the only one used as monotherapy and the other drugs that can be used in the combo treatments is good enough. Also know that in immunocompromised you gotta use like 5 drugs. The side effects of all the TB drugs is what I'd really focus on.

Just for practice: Which TB drug colors your body fluids red/orange and what is its MOA??

 

[Gauss]

rifampin
MOA: I don't care
haha

One thing that comes up in future shelfs/steps
HIV +
You need to check controls to determine if anergy exists, controls (MMR) should be +, assuming childhood vaccinations. Then you can go with ppd.
ppd doesn't indicate active disease, 2-3 induced sputums with acid fast staining
indurations 5,10,15
latent tb (ppd+) = INH 9 months (controversial 6-12 months?)
active -> depends on site pulmonary vs extrapulmonary which guides choice and duration
usually go with Rifamp, Ethamb, PZA, INH (Streptomycin, rifabutin)
At that point you're consulting ID anyways because of local susceptibility patterns, INH resistance exists

TB is very common - know it, love it. More than likely you'll end up ppd+ by the end of your 3rd or 4th year.