I know this question sounds awkward and a little scary, but it is actually a huge plus to be asked it at the beginning of an interview. It is your opportunity to bring up what you might like to talk about over the next 30 minutes or so and lay the foundations for an excellent and productive interview.
So, begin with... I'm Will/Wilma/Whatever, I grew up in rural Nebraska/ Brooklyn, NY/ Springfield, USA, and then proceed to cherry pick 3 or 4 great things about you that you would like to discuss with your interviewer. Could be volunteer experiences, could be academic strengths or research opportunities, could be your general motivations for medicine... it doesn't really matter just be sure they are engaging conversation topics that showcase your best healthcare career bound aspects. Gloss over the highlights of these 3 or 4 experiences (in a logical order) with a sentence or two about each. After you've concluded this summary of yourself, the interviewer will likely pick one of those topics you presented and go deeper with it.
In doing this you are sort of presenting a sampler platter of things they could choose to talk about. It is a great way to start.
Don't rehearse this too much, though. You want to seem genuine and natural, not canned.