Step I TH and estrogen

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Girfaroo

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10+ Year Member
Does someone have/have a reference to a concise explanation of how estrogen and thyroid hormones interact? I'm getting really confused.
 
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Estrogen increases synthesis of thyroid-binding globulin. Thus, during pregnancy total T4 increased, but it is increased due to bound T4, and free (unbound) T4 is in normal range, so that's why pregnant women don't have symptoms of hyperthyrodism.
 
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