Third Molars Agenesis

[slysnoodles]

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What are your thoughts?

Prevention of third molar tooth development in neonate rat with a long pulse diode laser.

Silvestri AR Jr, Mirkov MG, Connolly RJ.

Tufts University School of Dental Medicine, Boston, Massachusetts 02111.

BACKGROUND AND OBJECTIVES: Third molars (wisdom teeth) in humans have limited functional value and cause a high frequency of morbidity. A window of opportunity exists to stop their development. The purpose of this study is to evaluate whether a long pulse diode laser can selectively prevent third molar development in a rat animal model. STUDY DESIGN/MATERIALS AND METHODS: The study calculated theoretical diode laser parameters and irradiated 2- to 4-day-old rat pups in the posterior aspects of the oral cavity near the time of tooth bud initiation. Rats were sacrificed at 35-50 days and examined intraorally and radiographically for third molar development. Control and treated sides were compared histologically. RESULTS: Nearly half of the maxillary third molars and 80% of the mandibular third molars were selectively prevented from developing using a 20 W diode laser with infrequent, minor adverse effects on maxillary jaw growth. CONCLUSIONS: This study confirms the hypothesis that controlled, non-invasive laser treatment delivered on the surface of the oral mucosa near the site of tooth bud formation can selectively achieve third molar agenesis. It also offers hope that further innovative studies may bring about a safe, non-invasive laser treatment to selectively prevent third molar development in humans. Lasers Surg. Med. 35:385-391, 2004.

 

[delicious]

What are your thoughts?

Prevention of third molar tooth development in neonate rat with a long pulse diode laser.

Silvestri AR Jr, Mirkov MG, Connolly RJ.

Tufts University School of Dental Medicine, Boston, Massachusetts 02111.

BACKGROUND AND OBJECTIVES: Third molars (wisdom teeth) in humans have limited functional value and cause a high frequency of morbidity. A window of opportunity exists to stop their development. The purpose of this study is to evaluate whether a long pulse diode laser can selectively prevent third molar development in a rat animal model. STUDY DESIGN/MATERIALS AND METHODS: The study calculated theoretical diode laser parameters and irradiated 2- to 4-day-old rat pups in the posterior aspects of the oral cavity near the time of tooth bud initiation. Rats were sacrificed at 35-50 days and examined intraorally and radiographically for third molar development. Control and treated sides were compared histologically. RESULTS: Nearly half of the maxillary third molars and 80% of the mandibular third molars were selectively prevented from developing using a 20 W diode laser with infrequent, minor adverse effects on maxillary jaw growth. CONCLUSIONS: This study confirms the hypothesis that controlled, non-invasive laser treatment delivered on the surface of the oral mucosa near the site of tooth bud formation can selectively achieve third molar agenesis. It also offers hope that further innovative studies may bring about a safe, non-invasive laser treatment to selectively prevent third molar development in humans. Lasers Surg. Med. 35:385-391, 2004.

I feel badly for the rats that were "sacrificed." But at least they didn't have to worry about crowding.

You want my opinion: any study coming out of tufts is questionable at best.

 

[toofache32]

NOOOOOOOOOOOooooooooooooooooo!!!!!!!!!!!!

 

[delicious]

NOOOOOOOOOOOooooooooooooooooo!!!!!!!!!!!!

What?! You disagree with third molar research performed on rats at shoddy dental schools?

 

[adamlc18]

What?! You disagree with third molar research performed on rats at shoddy dental schools?

I don't think he is worried about that. I was kinda thinking the same thing myself. Where would this leave oral surgeons if this became standard treatment? Probably out of a job. 🙁

 

[12YearOldKid]

That is a pretty cool idea. Though it can't be good news for all the aspiring oral surgeons out there. 😉

 

[toofache32]

3rd molars exist for only one reason: to make a nice "clink" sound when they land in my bucket.

 

[River13]

3rd molars exist for only one reason: to make a nice "clink" sound when they land in my bucket.

...and to pay for the gas in my porsche...

 

[gpg]

I have a theory that all third molars,specially lowers, should be enucleated at the bud stage. remove the crown, clean up the membrane to prevent any cyst and relax. Naturlally not many people will afford it. But its much easier than getting a mesially impacted lower third molar out.

what say people?

 

[trypmo]

....
BACKGROUND AND OBJECTIVES: Third molars (wisdom teeth) in humans have limited functional value and cause a high frequency of morbidity.

MORBIDITY?!? Are they saying that a significant number of people actually die from having their wizzies grow in, or is "morbidity" referring to the teeth that have to come out (i.e. "die")?

From my experience with lasers I'd say that sending 20 Watts of coherent radiation down into tissues (unlike surgical lasers which are meant to cut through thin tissues or cut away top tissue layers) is generally considered not to be a good thing.

Plus, those "minor adverse effects on maxillary jaw growth" don't sound like too much fun.

Hmm, maybe I should just get the article. 😀

 

[toofache32]

MORBIDITY?!? Are they saying that a significant number of people actually die from having their wizzies grow in, or is "morbidity" referring to the teeth that have to come out (i.e. "die")?

From my experience with lasers I'd say that sending 20 Watts of coherent radiation down into tissues (unlike surgical lasers which are meant to cut through thin tissues or cut away top tissue layers) is generally considered not to be a good thing.

Plus, those "minor adverse effects on maxillary jaw growth" don't sound like too much fun.

Hmm, maybe I should just get the article. 😀

You're thinking of mortality, not morbidity.

 

[aphistis]

You're thinking of mortality, not morbidity.

What he said.

Morbidity is a generic term to indicate the presence of pathology, and I'm sure you're aware of the problems that can crop up from having janked-up wizzies.

Yes, "janked-up wizzies" is proper dental vocabulary, right alongside such terms as the universally-recognized "WFT amalgam."

 

[txdent2be2007]

Yes, "janked-up wizzies" is proper dental vocabulary, right alongside such terms as the universally-recognized "WFT amalgam."

"WFT amalgam?" Please explain!

 

[aphistis]

"WFT amalgam?" Please explain!

Whole f***ing tooth. 😉