D
One question that still has no answer is why is this guy on milrinone, too? That's very unusual, unless the patient has PHTN, which is probably caused by hypoxia/hypercarbia (on top of the pre-existing one from OSA), which is probably the reason for those humongous tidal volumes at a relatively low PEEP. PEEP of 10, when the belly is pressing upwards with much more than 10 cm of H2O, is a joke.Surgeon books a 147 KG EF 20% OHS/OSA pt w septic shock 103 fever on 20 ucg levo and primacor with bp 100/60 who is on peep 10 and FIO2 100% with RR 24 TV 600 on the vent for a trach. Surgeon won’t do it bedside (he isn't comfortable). He has been intubated for 20 days and his pulm wants me to do it. My concern is his PO2 will drop like a rock with the transport and eventually the switch leading me to have to recruit him back up w PPV and he will code at that point. Should have been done weeks ago but the wife was refusing.
I would die happy. And avoid acidosis, hypoxia and hypercarbia. You know.Well, if the echo estimated the pa pressure of 60, what would you do?
Just want to know if this is Biventricular failure or just left heart is all.
Anything else?
We had a 16yo dog with very symptomatic CHF. The vet put her on pimobendan which made her like a pup again. Bought her almost a year of excellent quality of life.
We had a 16yo dog with very symptomatic CHF. The vet put her on pimobendan which made her like a pup again. Bought her almost a year of excellent quality of life.
The OP didn’t mention anything about the right heart on his/her presentation.Then why not just look at the ventricular function on the echo and not mess with PAP estimates? You made the statement. Don't know what the hostility is all about...
The OP didn’t mention anything about the right heart on his/her presentation.
I wanted to get an idea of the whole picture.
RV function and PAP all go together. I read the whole report.
The Milrinone threw me off as I said in my first Post. Why in a septic patient?
Let's assume for a moment that the RV is failing (because of the PHTN). We also know that the LVEF is 20%. I don't know which is primary. Hence one would want appropriate preload, maintained/increased contractility without increased oxygen consumption, and maintained/decreased afterload with good coronary perfusion pressures for both. It's not easy.I think what people are getting at is that this gentleman is already obesity hypoventilation syndrome with an EF of 20%. PA numbers won't be the make or break in this situation because by definition he's already pulmonary hypertensive and right heart failed. The milrinone is an effort to lower the PAs and improve heart function despite the sepsis, therefore they added the levophed for vasoconstriction. The problem is levo increases PAP, so Vasopressin would've been a better choice.
This combined with the vent settings is why some say the best answer to situation is "find a better ICU doctor"
Let's assume for a moment that the RV is failing (because of the PHTN). We also know that the LVEF is 20%. I don't know which is primary. Hence one would want appropriate preload, maintained/increased contractility without increased oxygen consumption, and maintained/decreased afterload with good coronary perfusion pressures for both. It's not easy.
Milrinone plus vaso MAY have been the better combo. Or maybe epi plus vaso, or epi plus levo, or epi alone, or levo plus vaso, I have no idea how this patient responds. EVERY PATIENT IS DIFFERENT, regardless what the textbooks/studies say. But that's not what I didn't like in the management.
What I didn't like were the vent settings, and the fact that, even at FiO2 of 100%, the PEEP was a joke, the patient was not being proned, and the intensivist was concerned about getting a trach (which means he didn't even consider proning, among other things).
We did it at our hospital and we weren't that big a place. Not commonly though.Is it even common to do proning in the icu. none of the major hospitals ive rotated at did this.
Is it even common to do proning in the icu. none of the major hospitals ive rotated at did this.
It is a common (and proven) treatment of severe ARDS. Another proof that anesthesiology-CCM fellows should rotate through MICUs, because that's where the truly sick patients are.Is it even common to do proning in the icu. none of the major hospitals ive rotated at did this.
While in fellowship, we had an almost 400 lb-patient with severe ARDS and sepsis. He was on 2-3 pressors, a pain to ventilate. We proned him as a last resort (in a regular ICU bed). Almost immediately we were able to drop his FiO2 to 50% and his pressors. A few days later, while supine (and still on pressors), he self-extubated... successfully. We probably would not have had the guts yet. After a few more days he walked out of the hospital.NEJM - Error
Impressive but proning a critically ill 147kg patient is not without risk. Rotoprone limit is 160kg.
NEJM - Error
Impressive but proning a critically ill 147kg patient is not without risk. Rotoprone limit is 160kg.
I don't understand the point of proning if youre on vv ecmo
I think you prone to avoid going on VV ECMO. Try all the things of last resort to avoid ECMO.
I don't understand the point of proning if youre on vv ecmo
Well you still have to get off ECMO at some stage and proning can be part of the strategy to achieve this. Also being on ECMO doesn't guarantee oxygenation will be easy and there are a few reasons you might want to increase the contribution of the pts lungs towards oxygenation relative to that of the circuit.
No evidence that proning would aid with lung recovery. It may help with oxygenation but the underlying disease process doesn't get improved by proning, though you could make a stretch and say proning may help with clearing secretions. I can't understand a situation where you would remove someone from ECMO when they're still at a point where they need proning to maintain oxygenation.
I can't understand a situation where you would remove someone from ECMO when they're still at a point where they need proning to maintain oxygenation.
You are right, we don't have good trials to show improved mortality in ARDS from proning, except maaaaybe in some highly-selected populations (and those trials are debatable).No evidence that proning would aid with lung recovery. It may help with oxygenation but the underlying disease process doesn't get improved by proning, though you could make a stretch and say proning may help with clearing secretions. I can't understand a situation where you would remove someone from ECMO when they're still at a point where they need proning to maintain oxygenation.
That's interesting, we don't prone people on ECMO where I trained, not to say what you're proposing is necessarily wrong. I just allow lung rest but maintain enough PEEP that the lung still remains somewhat open. I'd be worried about decannulation during proning.I never said you would.
My comments were about the fact that even on ECMO you sometimes need to recruit lung and proning is part of the commonly used strategy used to achieve this.
That's interesting, we don't prone people on ECMO where I trained, not to say what you're proposing is necessarily wrong. I just allow lung rest but maintain enough PEEP that the lung still remains somewhat open. I'd be worried about decannulation during proning.
I've seen it done when they've been on for weeks with minimal improvement and CT shows some "recruitable lung".
And yeah the whole process of proning with cannulas in always made me nervous.
We have lots of ecmo. I have not seen a patient proned yet (it certainly may still happen when I'm not in the unit). Though, it certainly has been discussed on some of those patients.Did your hospitals do VV ECMO? If they are doing ECMO, they probably should be proning
That's interesting, we don't prone people on ECMO where I trained, not to say what you're proposing is necessarily wrong. I just allow lung rest but maintain enough PEEP that the lung still remains somewhat open. I'd be worried about decannulation during proning.