- Joined
- May 17, 2013
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Spoiler below, if you plan on taking this diagnostic at some point.
130. Which of the following initially binds to single-stranded DNA during replication?
A. Helicase
B. RNA Polymerase
C. DNA Polymerase III
D. DNA Ligase
Answer: B
...Did I completely miss something in my content review? Helicase and Ligase are immediately out because helicase doesn't directly bind DNA and DNA Ligase links only dsDNA, and cannot bind ssDNA. Since this is DNA replication, why will DNA Pol III not bind ssDNA? Why would RNA Pol even be involved?
130. Which of the following initially binds to single-stranded DNA during replication?
A. Helicase
B. RNA Polymerase
C. DNA Polymerase III
D. DNA Ligase
Answer: B
...Did I completely miss something in my content review? Helicase and Ligase are immediately out because helicase doesn't directly bind DNA and DNA Ligase links only dsDNA, and cannot bind ssDNA. Since this is DNA replication, why will DNA Pol III not bind ssDNA? Why would RNA Pol even be involved?