Step I TRH and Prolactin

[greenie]

So according to FA Thyroid Releasing Hormonre stimulates Prolactin release (p281 in 2009). Is this true? I never remember it really being emphasized in class. Is there a clinical correlation for this phenomenon? For example, would that mean that somebody with primary hypothyroidism and resulting elevated TRH would develop gynecomastia because of TRH stimulating prolactin?

 

[Mortal_Lessons]

So according to FA Thyroid Releasing Hormonre stimulates Prolactin release (p281 in 2009). Is this true? I never remember it really being emphasized in class. Is there a clinical correlation for this phenomenon? For example, would that mean that somebody with primary hypothyroidism and resulting elevated TRH would develop gynecomastia because of TRH stimulating prolactin?

👍 Yes, that's right. Also, look for lactation in a woman.

 

[Instatewaiter]

So according to FA Thyroid Releasing Hormonre stimulates Prolactin release (p281 in 2009). Is this true? I never remember it really being emphasized in class. Is there a clinical correlation for this phenomenon? For example, would that mean that somebody with primary hypothyroidism and resulting elevated TRH would develop gynecomastia because of TRH stimulating prolactin?

Yeah

Primary hypothyroidism can cause hyperprolactinemia. You would see galactorrhea in women and more likely decreased libido/impotence in men- if anything at all.

 

[FutureChiDoc]

I think a more important clinical correlation would be that primary hypothyroidism-->hyperprolactinemia would cause amenorrhea.

 

[512TA]

it is a good test for sheehan's postpartum necrosis.