types of hormones - hydrophillic v.s. hydrophobic!

[KlimtOphile]

Hi Everyone!

does anyone have a list of what category the hormones fall under? hydrophobic or hydrophilic? I know steroids are hydrophobic, and that epinephrine is an aa derived hydrophillic and insulin is a polypeptide hydrophillic -- how about theother ones???
also! i have PR test 4902 solutions only~ Can anyone give me a copy of the actual test? I lost it a while back when i took the PR course! Thanks !!!!!

Best of luck to everyone!!!!!

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[DrChandy]

Hi Everyone!

does anyone have a list of what category the hormones fall under? hydrophobic or hydrophilic? I know steroids are hydrophobic, and that epinephrine is an aa derived hydrophillic and insulin is a polypeptide hydrophillic -- how about theother ones???
also! i have PR test 4902 solutions only~ Can anyone give me a copy of the actual test? I lost it a while back when i took the PR course! Thanks !!!!!

Best of luck to everyone!!!!!

Just know the various hormones and what they do (and the mechanisms by which some of them function). If you are required to know about the hydrophilicity or hydrophobicity of a hormone, it will be presented to you in the context of a passage. Good luck.

 

[gotgame83]

Of the top of my head if its cholestrol based its phobic and if its peptide/amino based then its phillic. Some sample peptide based are like t3/t4 catacholamines hGH HCG etc

 

[SpyPuts]

Peptide hormones and the catecholamines (epinephrine, norepinephrine, MAYBE dopamine) are hydrophilic and act on target cells via a second messenger system. They are typically short-lived and fast acting when compared to non-polar hormones.

Non-polar hormones include the tyrosine-derivatives (T3 + T4, produced in thyroid) and steroids. These act at the transcriptional level, so their effects have a slower onset and are longer lasting. They diffuse through the cellular membrane and are carried into the nucleus by receptors. No secondary messenger system acts here.

One trick to keep in mind: only the thyroid produces hormones of 2 different types, T3 and T4 (tyrosine-derivatives) and calcitonin (a peptide). All other major endocrine system organs produce only one type of hormone:

Anterior pituitary: peptides
Posterior pituitary: trick question
Hypothalamus: peptides (ignore dopamine for the MCAT)
Adrenal cortex: steroids
Adrenal medulla: catecholamines
Parathyroid: peptide
Pancreas: peptides

 

[yunan]

per EK Bio study booklet:

***Hydrophillic (water soluble-dissolve in blood)***

- peptide hormones
1. anterior pituitary: FSH, LS, ACTH, hGH, TSH, Prolactin
2. posterior pituitary: ADH, oxytocin
3. parathyroid: PTH
4. pancreas: glucagon, insulin
5. thyroid: calcitonin

- tyrosine derivatives
1. adrenal medulla: epinephrine, norepinephrine


***Hydrophobic (lipid soluble-carried in blood by protein carrier - goes into cell nucleus)***

-steroid hormones
1. adrenal cortex: cortisol, aldosterone
2. gonad: estrogen, progesterone, testosterone

-tyrosine derivatives
1. thyroid: T3/T4

 

[KlimtOphile]

You guys ROCK!!!! Thanks for the responses.

absolutely scrumptrulescent baby...

Any questions, or any more responses, send em my way.