I interviewed at NEOUCOM my senior year in HS, back in 1999. I was accepted but i chose not to attend (mostly becuase i didnt want to be so close to home and wasnt completely sure i wanted to go to med school in the first place), but now im kicking myself in the ass for not at least having given it a bit more thought. The interview, for me, seemed quite difficult, but that was just becuase i totally wasnt prepared. They conduct the interview similar to any normal med school interview. I remember they asked in the app about your position on some relevant health care issue, so be prepared to talk a lot about that... also reasons for applying, wanting to be a doctor, commitment to service, etc. my best advice, is to review ur app and ur essays, look through their website, and keep current on that health care issue u wrote about. other than that just be comfortable and im sure u will do fine.