upper GI obstruction and jaundice
Started by Fungi121
I have never heard of this phenomenon
Like this?
It's unlikely that UGI obstruction would cause jaundice, and even LGI obstruction sees jaundice as a later complication.
It's unlikely that UGI obstruction would cause jaundice, and even LGI obstruction sees jaundice as a later complication.
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My 2 cents: it seems obvious that any obstruction that blocks the hepatopancreatic duct would lead to a backup of conjugated bilirubin into the bloodstream, however if there is an upper GI obstruction and conjugated bilirubin is not allowed to flow past, I believe it can be deconjugated by gut bacteria and then by virtue of being more lipid soluble can be reabsorbed via the GI mucosa leading to an eventual buildup of serum indirect bilirubin.
Biliary Obstruction Workup: Laboratory Studies, Imaging Studies, Procedures
Let me know what y'all think.
Biliary Obstruction Workup: Laboratory Studies, Imaging Studies, Procedures
Let me know what y'all think.
Yes! You are absolutely correct--I totally forgot about this. Thank you!
Deconjugation of bile acids by intestinal lactobacilli.
However, I would use this as example as an FYI for future reference, while sticking to post-hepatic obstruction as a cause of direct hyperbilirubinemia for exams.
I'll save it in my my head as an esoteric example so I can pimp future medstudents lol
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