Periopdoc : Why would you want to give a larger dose of a drug if you can get just the same effect with a smaller volume and change of technique?
Because minimal effective drug dosage is only one of the considerations I have when determining how I will perform a particular procedure. I also consider the time it will take me to perform the procedure, the risk that if my technique is suboptimal the results will be suboptimal, and most importantly the real and theoretical risks of using a higher dose.
If this were a study that demonstrated a smaller minimum effective dose of local anesthetic for cervical transforaminal injections or cervical sympathetic blocks, I would be "itching to try it out" even if it added 5-10 additional minutes to my block time. The therapeutic window is small enough to make dose the primary concern.
For an axillary block, minimizing the dose is really low on the priority list because the therapeutic window is so big. If a different technique takes an additional five minutes of time then it isn't worth it for such a low-risk procedure, especially if it ultimately turns out that the technique has suboptimal results for some patients.
If the findings of that article can be replicated consistently why not embrace the change?
Fallacious argument #1.
They have not been replicated yet, but if they are I will consider the results in the light of my above discussion on dosage/time/risk.
This study was not powered to answer the question "Is 1 ml of 2% Lidocaine per nerve sufficient for surgery on a population of individuals." That would require a much larger population, with more varied baseline characteristics, than the 11 patients that were ultimately enrolled in this study. This study was powered to determine the theoretical minimum dose that could be effective. It is a starting point, not a definitive study and thus I am not "itching to try it out."
I think that studies like this are very elegant. I also think that performing blocks with minimal local anesthetic is very elegant. However, it may not be practical for day to day implementation. I love elegant anesthesia when it works, but I prefer to be a practical anesthesiologist who uses elegant techniques when appropriate.
Do you give drugs to a patient just because you 'can' ?
Fallacious argument #2 (with snide overtones to boot)
but since you asked, I will bring up my own fallacious argument in response. The evidence suggests that 0.4 mg/kg of rocuronium is as effective at acheiving neuromuscular blockade as higher doses such as 0.9 or 1.2 mg/kg. Do you give more than 0.4 mg/kg rocuronium when starting a case? Why? Do YOU give drugs to a patient just because you can?
- pod