USMLE Question

[Kluver_Bucy]

Does

anyone know

what happens to GFR, RPF, TM, Filtration Fraction, Creatine Clearance if a person had one kidney rather than two?

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[Idiopathic]

As far as true renal phys goes, a person only needs 25% of total kidney mass to have a normal kidney profile. Assuming a person took care of hisself, all values should be normal.

However, that is rarely the case. Expect serum Cr values >1.5 as baseline in these people and everything else, expect for maybe filtration fraction, to be decreased (since it is a ratio of two things that are themselves decreased).

For boards though, you can be norma, functionally, with only one kidney.