Step I UTI Treatment

Started by chromuffin
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chromuffin

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7+ Year Member
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What is the typical treatment plan for UTIs? Here's what I know:

Nitrofurantoin if uncomplicated

TMP-SMX if complicated

But what if the patient has a sulfa allergy? What if TMP-SMX doesn't work?

Aminoglycosides or fluoroquinolones first?
Sorry this is a pretty obvious question but I just suck at pharm
 
What is the typical treatment plan for UTIs? Here's what I know:

Nitrofurantoin if uncomplicated

TMP-SMX if complicated

But what if the patient has a sulfa allergy? What if TMP-SMX doesn't work?

Aminoglycosides or fluoroquinolones first?
Sorry this is a pretty obvious question but I just suck at pharm
Pharma is not your problem
 
I deleted my original post, because I gave the recommendations for community-acquired pneumonia, rather than UTIs. But decided to post it anyways, considering that you're confused about UTI treatment, so it's likely that treatment guidelines for CA-P would be helpful for you as well. If not, then hopefully it'll help others.

outpatient
healthy: doxycycline or macrolide
comorbidities: fluoroquinolone, OR beta-lactam + macrolide

inpatient
(non-ICU)

fluoroquinolone, OR
beta-lactam + macrolid

inpatient (ICU)
beta-lactam + macrolide (IV), OR
beta-lactam + fluoroquinolone

This is per Uworld Step 2CK
 
Last edited:
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Something good to know is the distinction between uncomplicated vs. complicated UTI:
-- Male
-- child
-- advanced age
-- pregnant
-- DM
-- immunocompromised
-- recent antibiotic use
-- functional of anatomic abnormality of urinary tract
-- indwelling devices (foley)
-- hospital acquired
-- symptoms >7 days
 
What is the typical treatment plan for UTIs? Here's what I know:

Nitrofurantoin if uncomplicated

TMP-SMX if complicated

But what if the patient has a sulfa allergy? What if TMP-SMX doesn't work?

Aminoglycosides or fluoroquinolones first?
Sorry this is a pretty obvious question but I just suck at pharm

Ceftriaxone

Also fluoroquinolone resistance is expanding rapidly