Step I Uw id 1947

[winkleweizen]

So I understand that Phenoxybenzamine is a noncompetitive antagonist and would thus decrease Vmax, but why would it decrease potency (cause a rightward shift)? That really threw me off.

 

[jetspeeder]

So I understand that Phenoxybenzamine is a noncompetitive antagonist and would thus decrease Vmax, but why would it decrease potency (cause a rightward shift)? That really threw me off.

It doesn't, it is a mistake, I know some people who have gave feedback for that question.

The only possible scenario that can happen is if there are spare receptors, so the curve would shift right first and then when there are no more spare receptors the curve would then depress downwards.

 

[winkleweizen]

It doesn't, it is a mistake, I know some people who have gave feedback for that question.

The only possible scenario that can happen is if there are spare receptors, so the curve would shift right first and then when there are no more spare receptors the curve would then depress downwards.

thanks...imma add two pts to that blocks score now, hahaha