UWSE2 question ...SPOILER ALERT

Started by Saman49
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Saman49

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Can someone tell me amilodipine decrease preload or afterload?
FA says its like nitrate==>; decrease preload
Uwse says ==>; decrease afterload!
 
Can someone tell me amilodipine decrease preload or afterload?
FA says its like nitrate==>; decrease preload
Uwse says ==>; decrease afterload!

Dihydropyridine calcium-channel blockers notably decrease afterload, not preload.

Nitrates decrease preload in low doses and both preload and afterload in very high doses. Nitroprusside is the exception, which acts more significantly via afterload reduction (because it's very potent).
 
Dihydropyridine calcium-channel blockers notably decrease afterload, not preload.

Nitrates decrease preload in low doses and both preload and afterload in very high doses. Nitroprusside is the exception, which acts more significantly via afterload reduction (because it's very potent).

Thanks