Step I UWSE2 question ...SPOILER ALERT

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Saman49

Saman49

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10+ Year Member
Can someone tell me amilodipine decrease preload or afterload?
FA says its like nitrate==>; decrease preload
Uwse says ==>; decrease afterload!
 
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Saman49 said:
Can someone tell me amilodipine decrease preload or afterload?
FA says its like nitrate==>; decrease preload
Uwse says ==>; decrease afterload!
Click to expand...

Dihydropyridine calcium-channel blockers notably decrease afterload, not preload.

Nitrates decrease preload in low doses and both preload and afterload in very high doses. Nitroprusside is the exception, which acts more significantly via afterload reduction (because it's very potent).
 
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Phloston said:
Dihydropyridine calcium-channel blockers notably decrease afterload, not preload.

Nitrates decrease preload in low doses and both preload and afterload in very high doses. Nitroprusside is the exception, which acts more significantly via afterload reduction (because it's very potent).
Click to expand...

Thanks
 
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