I grew up in St. Louis and am doing my residency at WashU, and i would say that I would avoid buying in that area.
I agree with the others who have posted replies....if you are looking to buy within walking distance, I would look in the Central West End: specific streets would be: Laclede, West Pine, Maryland, McCausland. I would not go any further east than Grand, any further North than McCausland, and any further south of Forest Park Expressway.
A good place to look would be Union / Debalievere (sp?) and Waterman Blvd.
However, i just bought a house in St. Louis and prices in the CWE are quite pricey.
After having bought and sold my own homes, remember that the most important thing with real estate is location, location, and location.....people say that it is better to have the worst house in a good neighborhood, than to have the best house in a bad neighborhood.
Also, keep in mind that with St. Louis, people / real estate agents primarily search for homes based on School District, when it comes time for you to sell, you want to appeal to as many buyers as possible, and most people are not entralled with St. Louis City Schools.
If you are student, clayton is probably out of your price range. Good places to live that are still affordable are: Brentwood, Maplewood, Rock Hill, Webster Groves, Kirkwood.
Also, I am assuming that you are going to have a car (almost a must in St. Louis), if that is the case, keep in mind that Interstate 44 is where most of the affordable housing is, and traffic is a lot lighter on I-44 compared to I-64/40...personally, my new home is in Ballwin, MO about a 20 - 30 minute drive on I-44 to the medical center (I-44 exit at kingshighway, then north to kingshighway to the medical center (~2 miles on Kingshighway))....
One more thing, the Washington University Medical Center Housestaff Auxillary, publishes a pretty good guide that talks about where to live in St. Louis....you can find it here:
http://www.wumcha.com/WUMCHA_Welcome_Guide_2004-05_webversion.doc
Hope that helps...
If you have any other questions, feel free to PM me....