Goljan says that in Cushings, you get a weight gain due to hyperinsulinism in response to hyperglycemia that occurs with excess cortisol
But this doesn't seem to make sense to me physiologically. When I cross reference with Costanzo, she says the actions of cortisol include, decreased glucose utilization, decreased insulin sensitivity of adipose tissue, and increased lipolysis. But yet patients with Cushings present with weight gain
Can anyone clear up my confusion?
But this doesn't seem to make sense to me physiologically. When I cross reference with Costanzo, she says the actions of cortisol include, decreased glucose utilization, decreased insulin sensitivity of adipose tissue, and increased lipolysis. But yet patients with Cushings present with weight gain
Can anyone clear up my confusion?