I had a very similar story to yours. Instead it was my grandfather who had the complications. My PS was very compelling, but I had/have little to no shadowing experience. I also have never worked in a pharmacy. My interests were never in retail, so I didn't want to get involved in that. However, I've had a lot of life experiences and volunteer work that may have made me more appealing. My PCAT was a 72 and I have a 3.8 GPA. I applied early decision and was accepted to my number one choice.
Hope this helps. Good luck!